단백질의 도메인-도메인 간 상호작용 원자들의 밀도분포 분석

Abstract

The packing density of atoms constituting a protein has been studied as an important measure of protein structures to solve the problems such as docking and folding. Especially, the packing density of domain which is a separated subsection participating in function of the protein plays an essential role for understanding the cellular process. To calculate the packing density, it is important to calculate the precise volume of atomic region. The Voronoi diagram of atoms calculates volume of atomic region precisely with an atomic character and no computational errors, not like the previous methods. In this paper, the packing density of atoms constituting domain-domain interface was calculated via the Voronoi diagram of atoms and their distributions are analyzed. 1. 서