Rh(1)-Catalyzed Enantioselective Hydrogenayion of (E)-and (Z)-b-(Acylamino)acrylates using 1,4-Bisphosphine Ligands under Mild Conditions

Abstract

Rh-Me-BDPMI complex can be an effective catalyst for the hydrogenations of (E)-and (Z) -B-(acylamino)acrylates, in which the Z-isomers hydrogenated with the same or even higher ee values than the corresponding E-isomers. The conversion yield and enantioselectivity of (E)- and (Z)- isomers were CH2CI2, whereas the Z-isomers in polar MeOH solvent.