Core-shell structured molecularly imprinted materials for sensing applications
- Authors
- Bhogal, Shikha; Kaur, Kuldeep; Malik, Ashok Kumar; Sonne, Christian; Lee, Sang Soo; Kim, Ki-Hyun
- Issue Date
- Dec-2020
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Core-shell MIP particles; Molecular imprinting; Optical sensors; Electrochemical sensors; Surface imprinting techniques
- Citation
- TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v.133, pp.1 - 22
- Indexed
- SCIE
SCOPUS
- Journal Title
- TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Volume
- 133
- Start Page
- 1
- End Page
- 22
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/8164
- DOI
- 10.1016/j.trac.2020.116043
- ISSN
- 0165-9936
- Abstract
- Molecularly imprinted polymers (MIPs) are promising materials for analytical applications because of their structural predictability and recognition specificity. However, the applications of conventional MIPs suffer in a practical sense due to several defects (e.g., deeply embedded cavities, incomplete removal of the template, non-uniform distribution of binding sites, and slow rebinding kinetics). Core-shell nano particles coated with MIPs can be an attractive alternative to overcome such limitations. The core-shell structure offers a high surface area with a uniform distribution of binding sites to facilitate the removal of the template molecule and subsequent rebinding of the target molecule at high mass transfer efficiency. This work provides a comprehensive review of the classes of core-shell MIPs such as solid single, solid composite, and hollow core forms. The utility of novel and emerging core-shell MIPs is described for applications in optical, electrochemical, and piezoelectric sensors along with the associated challenges and opportunities.
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