Research trends for pipeline development in genome assembly
- Authors
- 정재희
- Issue Date
- 9-Mar-2015
- Publisher
- American Scientific Publishers
- Citation
- Advanced Science Letters, v.21, no.3, pp.225 - 228
- Journal Title
- Advanced Science Letters
- Volume
- 21
- Number
- 3
- Start Page
- 225
- End Page
- 228
- URI
- https://scholarworks.bwise.kr/hongik/handle/2020.sw.hongik/10093
- ISSN
- 1936-6612
- Abstract
- The genome research on analyzing the genetic information of diverse types of organisms has extended to human genome analysis after nucleotide sequencing had been developed for the first time by Frederick Sanger. The development of a next generation sequencing (NGS) technology has facilitated genome research from an organism with small to human with a large genome in size. Previously, the genome analysis was performed with the amplified DNA sequences by PCR technology. Their entire full-length sequence with fragments of nucleotide sequences was orderly determined by arrangement of fragments, but this method of genome research has a limitation of time and money. With the introduction of NGS technology the nucleotide sequencing is possible to do in parallel, requiring small amount of sample, which has enabled large genome analyses. In this review, recent trends for diverse genome pipelines are explored and discussed and the genome research necessity and its related technologies developed so far also briefly introduced. 짤 2015, American Scientific Publishers. All rights reserved.
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Collections - Department of General Studies > Department of General Studies > 1. Journal Articles
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