The Role of Adiponectin in the Skin
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oh Jieun | - |
dc.contributor.author | Lee Yeongyeong | - |
dc.contributor.author | Oh Sae-Woong | - |
dc.contributor.author | Li TianTian | - |
dc.contributor.author | Shin Jiwon | - |
dc.contributor.author | Park See-Hyoung | - |
dc.contributor.author | Lee Jongsung | - |
dc.date.accessioned | 2022-05-13T00:40:11Z | - |
dc.date.available | 2022-05-13T00:40:11Z | - |
dc.date.created | 2022-05-13 | - |
dc.date.issued | 2022-01-01 | - |
dc.identifier.issn | 1976-9148 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hongik/handle/2020.sw.hongik/27574 | - |
dc.description.abstract | Adiponectin (Ad), a 30 kDa molecule, is an anti-diabetic adipokine; although derived from adipose tissue, it performs numerous activities in various other tissues. It binds to its own receptors, namely adiponectin receptor 1(AdipoR1), adiponectin receptor 2 (AdipoR2), and T-cadherin (CDH13). Ad plays several roles, especially as a regulator. It modulates lipid and glucose metabolism and promotes insulin sensitivity. This demonstrates that Ad has a robust correlation with fat metabolism. Furthermore, although Ad is not in direct contact with other tissues, including the skin, it can be delivered to them by diffusion or secretion via the endocrine system. Recently it has been reported that Ad can impact skin cell biology, underscoring its potential as a therapeutic biomarker of skin diseases. In the present review, we have discussed the association between skin cell biology and Ad. To elaborate further, we described the involvement of Ad in the biology of various types of cells in the skin, such as keratinocytes, fibroblasts, melanocytes, and immune cells. Additionally, we postulated that Ad could be employed as a therapeutic target to maintain skin homeostasis. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 한국응용약물학회 | - |
dc.title | The Role of Adiponectin in the Skin | - |
dc.title.alternative | The Role of Adiponectin in the Skin | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park See-Hyoung | - |
dc.identifier.doi | 10.4062/biomolther.2021.089 | - |
dc.identifier.scopusid | 2-s2.0-85129731373 | - |
dc.identifier.wosid | 000834015700002 | - |
dc.identifier.bibliographicCitation | Biomolecules & Therapeutics, v.30, no.3, pp.221 - 231 | - |
dc.relation.isPartOf | Biomolecules & Therapeutics | - |
dc.citation.title | Biomolecules & Therapeutics | - |
dc.citation.volume | 30 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 221 | - |
dc.citation.endPage | 231 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.identifier.kciid | ART002834695 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | TOLL-LIKE RECEPTOR | - |
dc.subject.keywordPlus | TNF-ALPHA | - |
dc.subject.keywordPlus | FIBROBLAST HETEROGENEITY | - |
dc.subject.keywordPlus | HUMAN KERATINOCYTES | - |
dc.subject.keywordPlus | GLOBULAR FRAGMENT | - |
dc.subject.keywordPlus | ADIPOSE-TISSUE | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | MACROPHAGES | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | PSORIASIS | - |
dc.subject.keywordAuthor | Adiponectin | - |
dc.subject.keywordAuthor | Keratinocyte | - |
dc.subject.keywordAuthor | Melanocyte | - |
dc.subject.keywordAuthor | Fibroblast | - |
dc.subject.keywordAuthor | Innate immunity | - |
dc.subject.keywordAuthor | Adaptive immunity | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
94, Wausan-ro, Mapo-gu, Seoul, 04066, Korea02-320-1314
COPYRIGHT 2020 HONGIK UNIVERSITY. ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.