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Synthesis and antifungal activities of furoxan derivatives designed as novel fungicide
- Authors
- Hwang, K.-J.; Park, Y.C.; Kim, H.J.; Lee, J.H.
- Issue Date
- 1998
- Keywords
- Fungicidal activity; Furazan N-oxide; Furoxan; Wheat leaf rust
- Citation
- Bioscience, Biotechnology and Biochemistry, v.62, no.9, pp.1693 - 1697
- Journal Title
- Bioscience, Biotechnology and Biochemistry
- Volume
- 62
- Number
- 9
- Start Page
- 1693
- End Page
- 1697
- ISSN
- 0916-8451
- Abstract
- Furoxan derivatives 3-11 were designed and synthesized as potential fungicides. Symmetrically substituted furoxan derivatives 3a-j were prepared by dimerization of the corresponding nitrile oxide generated from N-hydroxyliminoyl chloride 2 in situ. Further functional group modifications of aldehyde 4, a key intermediate, generated furoxan derivatives 5-11. The fungicidal activities of furoxan derivatives 3-11 were observed over a broad spectrum of plant fungi at 250 ppm. © 1998, Taylor & Francis Group, LLC. All rights reserved.
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Related Researcher
- Hwang, Kwang Jin
- Science & Technology (Biological and Chemical Engineering)