Synthesis of 4H,6H-Furo[3,4-c]isoxazole Derivatives as New Potent Fungicides and Their Structure Activity Relationship
- Authors
- Kim, H.J.; Hwang, K.-J.; Lee, J.H.
- Issue Date
- 1997
- Citation
- Bulletin of the Korean Chemical Society, v.18, no.5, pp.534 - 540
- Journal Title
- Bulletin of the Korean Chemical Society
- Volume
- 18
- Number
- 5
- Start Page
- 534
- End Page
- 540
- URI
- https://scholarworks.bwise.kr/hongik/handle/2020.sw.hongik/27785
- ISSN
- 0253-2964
- Abstract
- 4H,6H-Furo[3,4-c]isoxazoles (I-IV), potential fungicides, have been designed and synthesized via intramolecular [2+3] cycloaddition of nitroalkyne 3 as a key step. The broad spectrum of fungicidal activities of furoisoxazoles (I-IV) were observed on plant pathogens at 250 ppm. Furoisoxazoles II, III with chlorophenyl at 6-position and methyl or alkylated oxime group at 3-position gave effective control of plant diseases. The furoisoxazole IV with a chlorophenyl group at 4-position also resulted in high fungicidal activities.
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Collections - College of Science and Technology > Department of Biological and Chemical Engineering > 1. Journal Articles
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