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Thermoresponsive, dually cross-linked elastin-like-polypeptide (ELP) micelle hydrogel with recovery propertiesThermoresponsive, dually cross-linked elastin-like-polypeptide (ELP) micelle hydrogel with recovery properties
- Other Titles
- Thermoresponsive, dually cross-linked elastin-like-polypeptide (ELP) micelle hydrogel with recovery properties
- Authors
- Choi, J.; Ryu, M.-C.; Kim, J.J.; Choi, S.-H.; Won, J.-I.
- Issue Date
- Aug-2023
- Publisher
- Springer
- Keywords
- Block Copolymer; Cross-linking; Elastin-like Polypeptides (ELPs); ELP-based Hydrogel
- Citation
- Korean Journal of Chemical Engineering, v.40, no.8, pp 1954 - 1962
- Pages
- 9
- Journal Title
- Korean Journal of Chemical Engineering
- Volume
- 40
- Number
- 8
- Start Page
- 1954
- End Page
- 1962
- ISSN
- 0256-1115
1975-7220
- Abstract
- Thermoresponsive protein-based hydrogels have been widely used due to their high potential in biomedical fields. Elastin-like polypeptides (ELPs) are one of the proteins that show lower critical solution temperature (LCST) behavior, resulting in self-assembly above critical micellular temperature (CMT). Here, we utilized ABC-type blocky ELPs to form hydrogels by introducing cross-linking sites, resulting in good mechanical properties. The hydrogels showed temperature-dependent viscoelasticity due to their structure change. Also, the recovery process of ELP-based hydrogels after large deformation is significantly dependent on the types of cross-linking (i.e., ionic, covalent, or ionic-covalent hybrid). © 2023, The Korean Institute of Chemical Engineers.
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Related Researcher
- Won, Jong in
- Engineering (Chemical Engineering)