Instrumentation for Time-of-Flight Positron Emission Tomography
- Authors
- Ullah, Muhammad Nasir; Pratiwi, Eva; Cheon, Jimin; Choi, Hojong; Yeom, Jung Yeol
- Issue Date
- Jun-2016
- Publisher
- SPRINGER HEIDELBERG
- Keywords
- Positron emission tomography; Time of flight; Instrumentation; Timing resolution
- Citation
- NUCLEAR MEDICINE AND MOLECULAR IMAGING, v.50, no.2, pp 112 - 122
- Pages
- 11
- Journal Title
- NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Volume
- 50
- Number
- 2
- Start Page
- 112
- End Page
- 122
- URI
- https://scholarworks.bwise.kr/kumoh/handle/2020.sw.kumoh/22013
- DOI
- 10.1007/s13139-016-0401-5
- ISSN
- 1869-3474
1869-3482
- Abstract
- Positron emission tomography (PET) is a molecular imaging modality that provides information at the molecular level. This system is composed of radiation detectors to detect incoming coincident annihilation gamma photons emitted from the radiopharmaceutical injected into a patient's body and uses these data to reconstruct images. A major trend in PET instrumentation is the development of time-of-flight positron emission tomography (ToF-PET). In ToF-PET, the time information (the instant the radiation is detected) is incorporated for image reconstruction. Therefore, precise and accurate timing recording is crucial in ToF-PET. ToF-PET leads to better localization of the annihilation event and thus results in overall improvement in the signal-to-noise ratio (SNR) of the reconstructed image. Several factors affect the timing performance of ToF-PET. In this article, the background, early research and recent advances in ToF-PET instrumentation are presented. Emphasis is placed on the various types of scintillators, photodetectors and electronic circuitry for use in ToF-PET, and their impact on timing resolution is discussed.
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- Appears in
Collections - School of Electronic Engineering > 1. Journal Articles
- Department of Medical IT Convergence Engineering > 1. Journal Articles
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