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Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia
- Authors
- Oh, Ji Hyun; Oh, Dong Jun; Koo, So-My; Kim, Yang Ki; Kim, Ki Up; Kim, Hyun Jo; Kim, Dong Won; Uh, Soo-Taek
- Issue Date
- Oct-2015
- Publisher
- 대한결핵및호흡기학회
- Keywords
- Cryptogenic Organizing Pneumonia; Clarithromycin; Macrolides; Adrenal Cortex Hormones
- Citation
- Tuberculosis and Respiratory Diseases, v.78, no.4, pp 401 - 407
- Pages
- 7
- Journal Title
- Tuberculosis and Respiratory Diseases
- Volume
- 78
- Number
- 4
- Start Page
- 401
- End Page
- 407
- ISSN
- 1738-3536
2005-6184
- Abstract
- Cryptogenic organizing pneumonia (COP) is an idiopathic interstitial pneumonia characterized by a subacute course and favorable prognosis with corticosteroids. However, some patients show resistance to steroids. Macrolides have been used with success in those patients showing resistance to steroids. A few reports showed treatment failure with macrolides in patients with COP who were resistant to steroids. In this report, we described two cases of COP who showed different responses to clarithromycin. One recovered completely, but the other gradually showed lung fibrosis with clarithromycin.
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Related Researcher
- Kim, hyeon jo
- College of Medicine (Department of Cardiovascular Surgery)