Comparison of treatment outcomes according to output voltage during shockwave lithotripsy for ureteral calculi: a prospective randomized multicenter study
- Authors
- Park, Jinsung; Kim, Hong-Wook; Hong, Sungwoo; Yang, Hee Jo; Chung, Hong
- Issue Date
- May-2015
- Publisher
- Springer Verlag
- Keywords
- Lithotripsy; Shock wave; Treatment outcome; Ureteral calculi
- Citation
- World Journal of Urology, v.33, no.5, pp 609 - 615
- Pages
- 7
- Journal Title
- World Journal of Urology
- Volume
- 33
- Number
- 5
- Start Page
- 609
- End Page
- 615
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/10687
- DOI
- 10.1007/s00345-014-1438-7
- ISSN
- 0724-4983
1433-8726
- Abstract
- To investigate the effect of fixed versus escalating voltage during SWL on treatment outcomes in patients with ureteral calculi (UC). A prospective, randomized, multicenter trial was conducted on 120 patients who were diagnosed with a single radiopaque UC. The patients were randomized into group C (n = 60, constant 13 kV, 3,000 shock wave, 2 Hz) or group E (n = 60, 11.4-12.0-13 kV per 1,000 shock waves, 2 Hz). They were evaluated by plain abdominal radiography and urinalysis at 1 week after a single session of SWL, and repeat SWL was performed if needed. The primary endpoint was stone-free rate at 1 week (SFR1) after SWL. Secondary endpoints were post-SWL visual pain score (VPS), oral analgesic requirements during 1 week, and cumulative SFRs after the second and third sessions of SWL. Groups C and E were well balanced in terms of baseline patients and stone characteristics, including pre-SWL VPS, stone location, and stone size (6.24 +/- A 1.92 vs. 6.30 +/- A 2.13 mm). SFR1s were not significantly different between groups C and E (60.0 vs. 68.3 %, p = 0.447). Analyses stratified by stone size (< 6 vs. a parts per thousand yen6 mm) showed no difference in SFR1 (p = 0.148 vs. 0.808). In the analyses stratified by stone location, group E tended to be more effective in distal UC (81.0 vs. 50.0 %, p = 0.052), whereas no difference was seen in proximal UC (p = 0.487). Secondary endpoints were also similar between the two groups. Our results suggest that voltage escalation during SWL in UC may not provide superior stone fragmentation compared to fixed voltage.
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