Comparison of the clinical characteristics and outcomes of Klebsiella pneumoniae and Streptococcus pneumoniae meningitis
- Authors
- Jung, Jiwon; Park, Ki-Ho; Park, Seong Yeon; Song, Eun Hee; Lee, Eun Jung; Choi, Seong-Ho; Choo, Eun Ju; Kwak, Yee Gyung; Sung, Heungsup; Kim, Sung-Han; Lee, Sang-Oh; Kim, Mi-Na; Kim, Yang Soo; Woo, Jun Hee; Choi, Sang-Ho
- Issue Date
- May-2015
- Publisher
- Elsevier BV
- Keywords
- Klebsiella pneumoniae; Streptococcus pneumoniae; Meningitis
- Citation
- Diagnostic Microbiology and Infectious Disease, v.82, no.1, pp 87 - 91
- Pages
- 5
- Journal Title
- Diagnostic Microbiology and Infectious Disease
- Volume
- 82
- Number
- 1
- Start Page
- 87
- End Page
- 91
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/10713
- DOI
- 10.1016/j.diagmicrobio.2015.02.006
- ISSN
- 0732-8893
1879-0070
- Abstract
- This multicenter, retrospective cohort study compared the clinical characteristics and outcomes of community-acquired Klebsiella pneumoniae meningitis (CA-KPM). with those of community-acquired Streptococcus pneumoniae meningitis (CA-SPM). Eighty-three adult patients, 27 with CA-KPM and 56 with CA-SPM, were included. Diabetes mellitus (48.1% versus 21.4%; P = 0.01) and liver cirrhosis (22.2% versus 5.4%; P = 0.05) were more commonly associated with CA-KPM. Comatose mental status (40.7% versus 12.5%; P = 0.01), septic shock (44.4% versus 8.9%; P < 0.001), and concomitant extrameningeal infections (40.7% versus 7.1%; P = 0.001) were also more common in the CA-KPM group. The 28-day mortality (44.4% versus 10.7%; P < 0.001) and inhospital mortality (51.9% versus 14.3%; P < 0.001) were higher in the CA-KPM group. In conclusion, diabetes mellitus and liver cirrhosis are more common in the CA-KPM patients who were also more likely to present with severe manifestations and poor outcomes. (C) 2015 Elsevier Inc. All rights reserved.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
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