Randomized Comparisons Between Different Stenting Approaches for Bifurcation Coronary Lesions With or Without Side Branch Stenosis
- Authors
- Kim, Young-Hak; Lee, Jae-Hwan; Roh, Jae-Hyung; Ahn, Jung-Min; Yoon, Sung-Han; Park, Duk-Woo; Lee, Jong-Young; Yun, Sung-Cheol; Kang, Soo-Jin; Lee, Seung-Whan; Lee, Cheol Whan; Seung, Ki Bae; Shin, Won-Yong; Lee, Nae-Hee; Lee, Bong-Ki; Lee, Sang-Gon; Nam, Chang-Wook; Yoon, Junghan; Yang, Joo-Young; Hyon, Min-Su; Lee, Keun; Jang, Jae-Sik; Kim, Hyun-Sook; Park, Seong-Wook; Park, Seung-Jung
- Issue Date
- 20-Apr-2015
- Publisher
- Elsevier BV
- Keywords
- bifurcation; coronary artery disease; restenosis; stent
- Citation
- JACC: Cardiovascular Interventions, v.8, no.4, pp 550 - 560
- Pages
- 11
- Journal Title
- JACC: Cardiovascular Interventions
- Volume
- 8
- Number
- 4
- Start Page
- 550
- End Page
- 560
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/10721
- DOI
- 10.1016/j.jcin.2015.01.016
- ISSN
- 1936-8798
1876-7605
- Abstract
- OBJECTIVES This study sought to evaluate the optimal percutaneous coronary intervention techniques using drug-eluting stents for bifurcation coronary lesions. BACKGROUND The optimal bifurcation stenting technique needs to be evaluated. METHODS The trial included 2 randomization studies separated by the presence of side branch (SB) stenosis for patients having non-left main bifurcation lesions. For 306 patients without SB stenosis, the routine final kissing balloon or leave-alone approaches were compared. Another randomization study compared the crush or single-stent approaches for 419 patients with SB stenosis. RESULTS Between the routine final kissing balloon and leave-alone groups for nondiseased SB lesions, angiographic restenosis occurred in 17.9% versus 9.3% (p = 0.064), comprising 15.1% versus 3.7% for the main branch (p = 0.004) and 2.8% versus 5.6% for the SB (p = 0.50) from 214 patients (69.9%) receiving 8-month angiographic follow-up. Incidence of major adverse cardiac events including death, myocardial infarction, or target vessel revascularization over 1 year was 14.0% versus 11.6% between the routine final kissing balloon and leave-alone groups (p = 0.57). In another randomization study for diseased SB lesions, 28.2% in the single-stent group received SB stents. From 300 patients (71.6%) receiving angiographic follow-up, between the crush and single-stent groups, angiographic restenosis rate was 8.4% versus 11.0% (p = 0.44), comprising 5.2% versus 4.8% for the main branch (p = 0.90) and 3.9% versus 8.3% for the SB (p = 0.12). One-year major adverse cardiac events rate between the crush and single-stent groups was 17.9% versus 18.5% (p = 0.84). CONCLUSIONS Angiographic and clinical outcomes were excellent after percutaneous coronary intervention using drug-eluting stents with any stent technique for non-left main bifurcation lesions once the procedure was performed successfully. (C) 2015 by the American College of Cardiology Foundation.
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