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Current advances related to Clostridium difficile infection

Authors
Kim, Yong GilJang, Byung Ik
Issue Date
Feb-2015
Publisher
Indian Council of Medical Research
Keywords
Clostridium difficile infection; Clostridium difficile vaccine; faecal microbiota transplantation
Citation
Indian Journal of Medical Research, v.141, pp 172 - 174
Pages
3
Journal Title
Indian Journal of Medical Research
Volume
141
Start Page
172
End Page
174
URI
https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/10893
ISSN
0971-5916
Abstract
Clostridium difficile infection (CDI) can trigger various responses, ranging from asymptomatic carriage to fulminant colitis. Hard-to-cure CDI, such as severe CDI, multiple recurrences of CDI, refractory CDI, and hypervirulent strains of C. difficile, require new treatments, although antibiotics such as metronidazole and vancomycin are the treatment of choice for initial and first relapsing CDI. Active immunization with C. difficile toxins and faecal microbiota transplantation deserve special attention. Here we describe these strategies for difficult-to-treat CDI.
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