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Successful Early Rituximab Treatment in a Case of Systemic Lupus Erythematosus with Potentially Fatal Diffuse Alveolar Hemorrhage
- Authors
- Na, Ju Ock; Chang, Sung Hae; Seo, Ki-Hyeon; Choi, Jae Sung; Lee, Ho Sung; Lyu, Ji Won; Nah, Seoung-Su
- Issue Date
- 2015
- Publisher
- Karger AG
- Keywords
- Systemic lupus erythematosus; Diffuse alveolar hemorrhage; Rituximab
- Citation
- Respiration; international review of thoracic diseases, v.89, no.1, pp 62 - 65
- Pages
- 4
- Journal Title
- Respiration; international review of thoracic diseases
- Volume
- 89
- Number
- 1
- Start Page
- 62
- End Page
- 65
- ISSN
- 0025-7931
1423-0356
- Abstract
- Diffuse alveolar hemorrhage (DAH) is a rare but devastating complication of systemic lupus erythematosus (SLE) with a high early mortality rate. DAH seldom occurs without active organ involvement. Recently, rituximab (RTX), a B cell-targeted therapy, has been reported to be effective for life-threatening autoimmune diseases. We describe a SLE patient who presented with acute respiratory failure due to DAH without other active organ involvement. This condition was dramatically improved with RTX without cyclophosphamide. (C) 2014 S. Karger AG, Basel
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
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Related Researcher
- Lee, Ho Sung
- College of Medicine (Department of Internal Medicine)