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Adenoid cystic carcinoma of the breast: Report of two cases with immunohistochemical profile of C-kit and MYB overexpression

Authors
Chin, SusieKim, Zisun
Issue Date
Oct-2014
Publisher
Indian Association of Pathologists and Microbiologists
Keywords
Adenoid cystic carcinoma; breast; C-kit; MYB; immunohistochemistry
Citation
Indian Journal of Pathology and Microbiology, v.57, no.4, pp 611 - 613
Pages
3
Journal Title
Indian Journal of Pathology and Microbiology
Volume
57
Number
4
Start Page
611
End Page
613
URI
https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/11811
DOI
10.4103/0377-4929.142693
ISSN
0377-4929
0974-5130
Abstract
Adenoid cystic carcinoma (ACC) is a rare tumor with characteristic histologic features. Staining with basal markers for estrogen receptor, progesterone receptor, and HER2 usually shows negative results. Immunohistochemical analysis of C-kit and MYB overexpression of the ACC also has been reported. We report two cases of ACC of the breast with C-kit and MYB overexpression that clinically confirm these previously reported characteristics and suggest that further molecular study of the expression of these two proteins can lead to future therapeutic strategies.
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