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Gold nanoparticles in breast cancer treatment: Promise and potential pitfalls
- Issue Date
- 28-May-2014
- Publisher
- Elsevier BV
- Keywords
- Gold nanoparticle; Breast neoplasms; Theranostics; Nanotechnology
- Citation
- Cancer Letters, v.347, no.1, pp 46 - 53
- Pages
- 8
- Journal Title
- Cancer Letters
- Volume
- 347
- Number
- 1
- Start Page
- 46
- End Page
- 53
- ISSN
- 0304-3835
1872-7980
- Abstract
- Despite remarkable achievements in the treatment of breast cancer, some obstacles still remain. Gold nanoparticles may prove valuable in addressing these problems owing to their unique characteristics, including their enhanced permeability and retention in tumor tissue, their light absorbance and surface plasmon resonance in near-infrared light, their interaction with radiation to generate secondary electrons, and their ability to be conjugated with drugs or other agents. Herein, we discuss some basic concepts of gold nanoparticles, and early results from studies regarding their use in breast cancer, including toxicity and side effects. We also discuss these particles' potential clinical applications. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
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Collections - College of Medicine > Department of General Surgery > 1. Journal Articles
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Related Researcher
- Lee, Ji hyoun
- College of Medicine (Department of General Surgery)