Asymmetric Synthesis of Tetrahydroquinolines via Saegusa-type Oxidative Enamine Catalysis/1,5-Hydride Transfer/Cyclization Sequences
- Authors
- Suh, Chang Won; Woo, Saet Byeol; Kim, Dae Young
- Issue Date
- Apr-2014
- Publisher
- Wiley - VCH Verlag GmbH & Co. KG
- Keywords
- aldehydes; 1; 5-hydride transfer; oxidative enamine catalysis; Saegusa oxidation; tetrahydroquinolines
- Citation
- Asian Journal of Organic Chemistry, v.3, no.4, pp 399 - 402
- Pages
- 4
- Journal Title
- Asian Journal of Organic Chemistry
- Volume
- 3
- Number
- 4
- Start Page
- 399
- End Page
- 402
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/12292
- DOI
- 10.1002/ajoc.201400022
- ISSN
- 2193-5807
2193-5815
- Abstract
- Enantioselective organocatalytic synthesis of tetrahydroquinolines has been achieved via Saegusa-type oxidative enamine catalysis/1,5-hydride transfer/cyclization sequences. The feature of this research is a one-pot transformation of 3-aryl aldehydes into tetrahydroquinolines by using environmentally benign catalytic Saegusa oxidation and highly efficient internal redox reactions. The synthetically useful ring-fused tetrahydroquinoline derivatives were obtained in moderate yields and high levels of enantioselectivity.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Natural Sciences > Department of Chemistry > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/12292)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.