Gadoxetic acid-enhanced MRI for T-staging of gallbladder carcinoma: emphasis on liver invasion
- Authors
- Hwang, J.; Kim, Y. K.; Choi, D.; Rhim, H.; Lee, W. J.; Hong, S. S.; Kim, H-J; Chang, Y-W
- Issue Date
- Jan-2014
- Publisher
- British Institute of Radiology
- Keywords
- Gadoxetic acid-enhanced MRI for T-staging of gallbladdercarcinoma: emphasis on liver invasion
- Citation
- British Journal of Radiology, v.87, no.1033
- Journal Title
- British Journal of Radiology
- Volume
- 87
- Number
- 1033
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/12563
- DOI
- 10.1259/bjr.20130608
- ISSN
- 0007-1285
1748-880X
- Abstract
- Objective: To evaluate the diagnostic performance of gadoxetic acid-enhanced MRI with an emphasis on the usefulness of the hepatobiliary phase (HBP) in T-staging of gallbladder carcinoma. Methods: 66 patients with surgically confirmed gallbladder carcinoma underwent MRI. Two radiologists independently reviewed two sets of gadoxetic acid-enhanced MRI without and with the HBP. Local tumour spread was evaluated according to T-staging, and the results were compared with pathological findings. The diagnostic performance of two image sets to differentiate each T-stage was compared. Results: The sensitivities of MRI with the HBP to differentiate T1 vs >= T2 lesions, <= T2 vs >= T3 lesions and <= T3 vs T4 lesions were 96.3%, 85.7% and 100% for Observer 1 and 92.6%, 95.2% and 100% for Observer 2, respectively (p < 0.0001). By adding the HBP, the sensitivities to differentiate <= T2 vs >= T3 lesions were increased from 66.7% to 85.7% for Observer 1 and from 81.0% to 95.2% for Observer 2, although there was no significant difference (p > 0.05). The overall accuracies for T-staging were increased from 80.3% to 86.4% for Observer 1, a statistically significant degree (p = 0.046), and from 83.8% to 87.9% for Observer 2 (p > 0.05). The k-value for the two observers indicated excellent agreement. Conclusion: Gadoxetic acid-enhanced MRI provided acceptable diagnostic performance for T-staging of gallbladder carcinoma. Addition of the HBP aids in the detection of liver invasion. Advances in knowledge: In the T-staging of gallbladder carcinoma, gadoxetic acid-enhanced MRI with the HBP may enhance detection of liver invasion.
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Collections - College of Medicine > Department of Radiology > 1. Journal Articles
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