Elevated Aurora Kinase A Protein Expression in Diabetic Skin Tissue
DC Field | Value | Language |
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dc.contributor.author | Cho, Moon Kyun | - |
dc.contributor.author | An, Je Min | - |
dc.contributor.author | Kim, Chul Han | - |
dc.contributor.author | Kang, Sang Gue | - |
dc.date.accessioned | 2021-08-11T23:27:20Z | - |
dc.date.available | 2021-08-11T23:27:20Z | - |
dc.date.issued | 2014-01 | - |
dc.identifier.issn | 2234-6163 | - |
dc.identifier.issn | 2234-6171 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/12599 | - |
dc.description.abstract | Background Aurora kinase A (Aurora-A) plays an important role in the regulation of mitosis and cytokinesis. Dysregulated Aurora-A leads to mitotic faults and results in pathological conditions. No studies on Aurora-A expression in human diabetic skin tissue have been reported. In light of this, we explored the expression of Aurora-A in human diabetic skin tissue. Methods Aurora-A protein was evaluated by western blotting in 6 human diabetic skin tissue and 6 normal skin specimens. Results Increased expression of Aurora-A protein was detected in all diabetic skin tissue samples in both western blot analysis and immunohistochemical staining. However, in the case of the normal skin tissue, no bands of Aurora-A protein were detected in either the western blotting analysis or the immunohistochemical staining. Conclusions Thus far, there have been no studies on the expression of Aurora-A in diabetic skin tissue. However, we believe that oxidative DNA damage related to the expression of Aurora-A protein and Aurora-A could be involved inhuman diabetic skin tissue. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한성형외과학회 | - |
dc.title | Elevated Aurora Kinase A Protein Expression in Diabetic Skin Tissue | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.5999/aps.2014.41.1.35 | - |
dc.identifier.scopusid | 2-s2.0-84893336778 | - |
dc.identifier.wosid | 000219270800006 | - |
dc.identifier.bibliographicCitation | Archives of Plastic Surgery, v.41, no.1, pp 35 - 39 | - |
dc.citation.title | Archives of Plastic Surgery | - |
dc.citation.volume | 41 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 35 | - |
dc.citation.endPage | 39 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001844921 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordAuthor | Skin | - |
dc.subject.keywordAuthor | Diabetes mellitus | - |
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