The Risk Factors for Bleeding of Fundal Varices in Patients with Liver Cirrhosis
- Authors
- Park, Eui Ju; Jang, Jae Young; Lee, Ji Eun; Jeong, Soung Won; Lee, Sae Hwan; Kim, Sang Gyune; Cha, Sang-Woo; Kim, Young Seok; Cho, Young Deok; Cho, Joo Young; Kim, Hong Soo; Kim, Boo Sung; Kim, Yong Jae
- Issue Date
- Nov-2013
- Publisher
- 거트앤리버 발행위원회
- Keywords
- Cirrhosis; Hypertension, portal; Hepatic venous pressure gradient; Fundal varices; Portasystemic shunt, surgical
- Citation
- Gut and Liver, v.7, no.6, pp 704 - 711
- Pages
- 8
- Journal Title
- Gut and Liver
- Volume
- 7
- Number
- 6
- Start Page
- 704
- End Page
- 711
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13258
- DOI
- 10.5009/gnl.2013.7.6.704
- ISSN
- 1976-2283
2005-1212
- Abstract
- Background/Aims: The relationship between portal hemodynamics and fundal varices has not been well documented. The purpose of this study was to understand the pathophysiology of fundal varices and to investigate bleeding risk factors related to the presence of spontaneous portosystemic shunts, and to examine the hepatic venous pressure gradient (HVPG) between fundal varices and other varices. Methods: In total, 85 patients with cirrhosis who underwent HVPG and gastroscopic examination between July 2009 and March 2011 were included in this study. The interrelationship between HVPG and the types of varices or the presence of spontaneous portosystemic shunts was studied. Results: There was no significant difference in the HVPG between fundal varices (n=12) and esophageal varices and gastroesophageal varices type 1 (GOV1) groups (n=73) (17.1+/-7.7 mm Hg vs 19.7+/-5.3 mm Hg). Additionally, there was no significant difference in the HVPG between varices with spontaneous portosystemic shunts (n=28) and varices without these shunts (n=57) (18.3+/-5.8 mm Hg vs 17.0+/-8.1 mm Hg). Spontaneous portosystemic shunts increased in fundal varices compared with esophageal varices and GOV1 (8/12 patients [66.7%] vs 20/73 patients [27.4%]; p=0.016). Conclusions: Fundal varices had a high prevalence of spontaneous portosystemic shunts compared with other varices. However, the portal pressure in fundal varices was not different from the pressure in esophageal varices and GOV1.
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Collections - College of Medicine > Department of Radiology > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
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