Correlation between serum 25-hydroxyvitamin D levels and methicillin - resistant Staphylococcus aureus skin colonization in atopic dermatitis
DC Field | Value | Language |
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dc.contributor.author | Min, Taek Ki | - |
dc.contributor.author | Yang, Hyeon Jong | - |
dc.contributor.author | Lee, Hae Won | - |
dc.contributor.author | Pyun, Bok Yang | - |
dc.date.accessioned | 2021-08-12T01:16:49Z | - |
dc.date.available | 2021-08-12T01:16:49Z | - |
dc.date.issued | 2013-06 | - |
dc.identifier.issn | 2288-0402 | - |
dc.identifier.issn | 2288-0410 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13684 | - |
dc.description.abstract | Purpose: Bacterial infection with Staphylococcus aureus is a common complication of atopic dermatitis (AD) and involved in the worsening of this disease. Recent studies have revealed an increasing prevalence of community-associated methicillin-resistant S. aureus (MRSA) among patients with AD and the role of vitamin D in the immunopathogenesis of AD. We carried out a study to see whether levels of vitamin D correlate with MRSA skin colonization in AD. Methods: Total 60 patients with AD aged between 3 months and 6 years old were enrolled. We measured disease severity using the Scoring Atopic Dermatitis (SCORAD) index, serum levels of 25-hydroxyvitamin D (25(OH) D), total immunoglobulin E levels, eosinophil cationic protein and bacterial colonization by skin swab and culture method. Results: S. aureus was cultured in 20 patients of the total (33.3%). MRSA was comprised 35% of the S. aureus- positive group. SCORAD value was significantly higher in S. aureus- positive group. Serum levels (mean +/- standard deviation) of 25( OH) D were lower in MRSA group (22.6 +/- 11.5 ng/mL) compared with those of methicillin- sensitive S. aureus group (31.3 +/- 10.2 ng/mL) or S. aureus negative group (34.3 +/- 15.8 ng/mL). But there was no statistically significant difference. Conclusion: Our study shows that the serum levels of 25(OH) D were lower in MRSA group. But there was no statistically significant difference. Therefore further studies including large numbers of cases are necessary. | - |
dc.format.extent | 6 | - |
dc.language | 한국어 | - |
dc.language.iso | KOR | - |
dc.publisher | 대한 소아알레르기 호흡기학회 | - |
dc.title | Correlation between serum 25-hydroxyvitamin D levels and methicillin - resistant Staphylococcus aureus skin colonization in atopic dermatitis | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.4168/aard.2013.1.2.138 | - |
dc.identifier.wosid | 000218621400007 | - |
dc.identifier.bibliographicCitation | Allergy Asthma & Respiratory Diseases, v.1, no.2, pp 138 - 143 | - |
dc.citation.title | Allergy Asthma & Respiratory Diseases | - |
dc.citation.volume | 1 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 138 | - |
dc.citation.endPage | 143 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001778356 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Allergy | - |
dc.relation.journalWebOfScienceCategory | Allergy | - |
dc.subject.keywordPlus | VITAMIN-D | - |
dc.subject.keywordPlus | 1,25-DIHYDROXYVITAMIN D-3 | - |
dc.subject.keywordPlus | ANTIMICROBIAL PEPTIDES | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | INFECTIONS | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | ASTHMA | - |
dc.subject.keywordAuthor | Vitamin D | - |
dc.subject.keywordAuthor | Methicillin-resistant Staphylococcus aureus | - |
dc.subject.keywordAuthor | Atopic dermatitis | - |
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