Acute eosinophilic pneumonia related to a mesalazine suppository
- Authors
- Kim, Jung Hyun; Lee, June-Hyuk; Koh, Eun-Suk; Park, Sung Woo; Jang, An-Soo; Kim, Dojin; Park, Choon-Sik
- Issue Date
- Apr-2013
- Publisher
- Asia Pacific Association of Allergy, Asthma and Clinical Immunology
- Keywords
- Eosinophilic pneumonia; Bronchiolitis obliterans with organizing pneumonia; Mesalazine; Suppository
- Citation
- Asia Pacific Allergy, v.3, no.2, pp 136 - 139
- Pages
- 4
- Journal Title
- Asia Pacific Allergy
- Volume
- 3
- Number
- 2
- Start Page
- 136
- End Page
- 139
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13819
- DOI
- 10.5415/apallergy.2013.3.2.136
- ISSN
- 2233-8268
- Abstract
- It has been well known that mesalazine can cause the interstitial lung disease, such as Bronchiolitis obliterans with organizing pneumonia (BOOP), Non-Specific Interstitial Pneumonia (NSIP), or eosinophilic pneumonia. 5-Aminosalicylic acid (5-ASA), mesalazine, and sulfasalazine are important drugs for treating inflammatory bowel disease. Topical products of these limited systemic absorption and have less frequent side effects, therefore suppository form of these drugs have been used more than systemic drug. Most cases of measalzine-induced lung toxicity develop from systemic use of the drug. A 30-year-old woman had an interstitial lung disease after using mesalazine suppository because of ulcerative colitis. The lung biopsy demonstrated eosinophilic pneumonia combined with BOOP. She was recovered after stopping of mesalazine suppository and treatment with systemic steroid.
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- Appears in
Collections - College of Medicine > Department of Pathology > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
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