Gynecologic complication of chronic graft-versus-host disease: Vaginal obstructionGynecologic complication of chronic graft-versus-host disease: Vaginal obstruction
- Other Titles
- Gynecologic complication of chronic graft-versus-host disease: Vaginal obstruction
- Authors
- 박준식; 김태희; 이해혁; 정수호; 이대근
- Issue Date
- 2013
- Publisher
- 대한산부인과학회
- Keywords
- Graft vs host disease; Hematocolpos; Peripheral blood stem cell transplantation; Vagina
- Citation
- Obstetrics & Gynecology Science, v.56, no.04, pp 277 - 280
- Pages
- 4
- Journal Title
- Obstetrics & Gynecology Science
- Volume
- 56
- Number
- 04
- Start Page
- 277
- End Page
- 280
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/14324
- DOI
- 10.5468/ogs.2013.56.4.277
- ISSN
- 2287-8572
2287-8580
- Abstract
- Allogenic peripheral blood stem cell transplantation (Allo-PBSCT) is being used to treat hematological malignancies with increasing frequency. Graft-versus-host disease (GvHD) is a complex complication of PBSCT. A 43-year-old woman came to the gynecology clinic for amenorrhea. She had been diagnosed with acute myeloid leukemia 2 years earlier and treated with induction and consolidation chemotherapy. After developing complete remission, she underwent Allo-PBSCT. When she started chemotherapy, her menstrual cycle completely disappeared. Fourteen months after menopausal hormone replacement therapy, it was discovered that her upper vaginal canal was completely obstructed. The lower vagina had an atrophic appearance. We report a rare case of partial vaginal obstruction as a complication of chronic GvHD and review the literature. We expect that this case report provides an opportunity to remind clinician of the gynecologic complications of GvHD.
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Collections - College of Medicine > Department of Obstetrics and Gynecology > 1. Journal Articles
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