폐암 환자에서 Docetaxel 항암 요법 치료 후 발생한 피부경화증 1예A Case of Skin Sclerosis Associated with Docetaxel Chemotherapy for Non-Small Cell Lung Cancer
- Other Titles
- A Case of Skin Sclerosis Associated with Docetaxel Chemotherapy for Non-Small Cell Lung Cancer
- Authors
- 남재형; 문종주; 이준혁; 박성우; 장안수; 김도진; 전찬홍; 고은석
- Issue Date
- 2013
- Publisher
- 대한류마티스학회
- Keywords
- Docetaxel; Scleroderma; Lung cancer; Adverse effect
- Citation
- 대한류마티스학회지, v.20, no.3, pp 198 - 201
- Pages
- 4
- Journal Title
- 대한류마티스학회지
- Volume
- 20
- Number
- 3
- Start Page
- 198
- End Page
- 201
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/14331
- ISSN
- 2093-940X
2233-4718
- Abstract
- A 64-year-old woman was diagnosed with non-small cell lung cancer. Her disease was stage 4 (T2N2M1) with squamous cell carcinoma. She had been treated with docetaxel and carboplatin. After a completion of 11 cycle of chemotherapy, edema appeared on both feet and had spread rapidly up to the pretibial area without response to diuretics. Sclerotic changes and pigmentation followed but both knees and other parts of the body were spared. There was no evidence of vascular occlusions. On serologic tests, antinuclear, anti-centromere, and anti-topoisomerase I antibodies were all negative. A skin biopsy revealed diffuse infiltration of lymphocytes and discretely thickened collagen bundles in the superficial dermis. After discontinuing docetaxel chemotherapy, she was treated with prednisolone and D-penicillamine and sclerotic changes on the lower legs were improved.
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Collections - College of Medicine > Department of Pathology > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
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