수면의 질과 비현훈어지럼 간의 연관성: 병원기반 환자-대조군 연구

Abstract

Objectives: Poor sleep quality causes various daytime function impairments like fatigue and daytime sleepiness. Dizziness is a common presenting complaint and may be attributed broadly to a number of underlying disorders. However, studies on the sleep quality in patient with dizziness still remain. We hypothesized the patients with poor quality of sleep may have a non-vertiginous dizziness (NVD).The aim was to investigate the association between the quality of sleep and the patients with NVD. Methods: We investigated 106 patients who had presented NVD in neurology department and no major medical, psychiatric, and neurological disorders so that they completed the following questionnaires: the Pittsburgh Sleep Quality Index (PSQI), the Insomnia Severity Index (ISI), the Fatigue Severity Index (FSS), the Epworth Sleepiness Scale (ESS), Sleep Apnea scale of the Sleep Disorders Questionnaire (SA- SDQ) and Beck Depression Inventory (BDI). 116 dizziness-free controls were recruited via Health Screening Center and also completed the same questionnaires. Results: Patient with NVD had significantly higher PSQI and ISI score compared with the controls (PSQI: 7.7±4.4 vs. 5.4±2.6, p<0.001, ISI: 9.7±7.0 vs. 6.8±4.4, p<0.001). In multiple logistic regression analysis adjusted for age, sex, BMI, and BDI, poor sleep quality was significantly associated with NVD. Fully adjusted odds ratio for NVD associated with 1 unit increase in PSQI was 1.15 (95% CI: 1.04-1.26). After adjusted for age, sex, and BMI, people with insomnia (ISI≥15) was significantly associated with NVD (OR=4.43, 95% CI: 1.66-11.81). Conclusions: This study suggests that the poor quality of sleep is associated with NVD.