Bortezomib Induced Tumor Lysis Syndrome in Multiple MyelomaBortezomib Induced Tumor Lysis Syndrome in Multiple Myeloma
- Other Titles
- Bortezomib Induced Tumor Lysis Syndrome in Multiple Myeloma
- Authors
- 유시내; 류성우; 김경하; 김세형; 이남수; 박성규; 원종호
- Issue Date
- 2013
- Publisher
- 순천향의학연구소
- Keywords
- Bortezomib; Multiple myeloma; Tumor lysis syndrome
- Citation
- Soonchunhyang Medical Science, v.19, no.1, pp 31 - 33
- Pages
- 3
- Journal Title
- Soonchunhyang Medical Science
- Volume
- 19
- Number
- 1
- Start Page
- 31
- End Page
- 33
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/14402
- ISSN
- 2233-4289
- Abstract
- The tumor lysis syndrome (TLS) commonly occurs in the lymphoproliferative disorder, either spontaneously or in response to therapy.
TLS is uncommon in multiple myeloma. However, with the use of bortezomib in the treatment of multiple myeloma, cases of TLS have been reported. We report here threepatients who presented with TLS after the administration of bortezomib. Two of them presented mild symptoms and recovered with hydration only. However, death of the other patient was associated with TLS. We should monitor patients who had high tumor burden, especially in early phase of bortezomib therapy and appropriate prophylaxis for high risk patient is also needed.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
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