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Catalytic enantioselective bromolactonization of alkenoic acids in the presence of palladium complexes
- Authors
- Lee, Hyun Joo; Kim, Dae Young
- Issue Date
- 19-Dec-2012
- Publisher
- Elsevier BV
- Keywords
- Asymmetric catalysis; Chiral palladium catalysts; Bromolactonization; gamma-Lactones; Alkenoic acids
- Citation
- Tetrahedron Letters, v.53, no.51, pp 6984 - 6986
- Pages
- 3
- Journal Title
- Tetrahedron Letters
- Volume
- 53
- Number
- 51
- Start Page
- 6984
- End Page
- 6986
- ISSN
- 0040-4039
- Abstract
- The catalytic enantioselective bromolactonization of alkenoic acids promoted by chiral palladium complexes has been developed, allowing facile synthesis of the corresponding gamma-lactones with excellent enantioselectivity (up to 97% ee). The method reported represents a practical entry for the preparation of chiral gamma-lactone derivatives. (C) 2012 Elsevier Ltd. All rights reserved.
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Related Researcher
- Kim, Dae Young
- College of Natural Sciences (Department of Chemistry)