Effect of Epidural Magnesium on the Incidence of Chronic Postoperative Pain After Video-Assisted Thoracic Surgery
- Authors
- Lee, Joon-Ho; Yang, Woo-Dae; Han, Seong-Yeup; Noh, Jeong-Il; Cho, Seong-Hwan; Kim, Sang-Hyun; Chae, Won-Seok; Jin, Hee-Cheol
- Issue Date
- Dec-2012
- Publisher
- W. B. Saunders Co., Ltd.
- Keywords
- epidural magnesium; chronic postoperative pain; video-assisted thoracic surgery
- Citation
- Journal of Cardiothoracic and Vascular Anesthesia, v.26, no.6, pp 1055 - 1059
- Pages
- 5
- Journal Title
- Journal of Cardiothoracic and Vascular Anesthesia
- Volume
- 26
- Number
- 6
- Start Page
- 1055
- End Page
- 1059
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/14669
- DOI
- 10.1053/j.jvca.2012.06.020
- ISSN
- 1053-0770
1532-8422
- Abstract
- Objective: The aim of this study was to determine whether the epidural administration of magnesium during the perioperative period decreased the incidence of chronic postoperative pain (CPOP) at 3 months after video-assisted thoracic surgery. Design: Prospective, randomized, and blinded. Setting: A university hospital. Participants: Patients. Interventions: Before the induction of anesthesia, the patients were assigned randomly to receive normal saline, 5 mL, (group C, n = 72) or magnesium sulfate, 100 mg (group M, n = 72), epidurally. At the end of surgery, group C received a continuous infusion of a mixture of 0.2% ropivacaine, 226 mL, and fentanyl, 1,200 mu g, through a patient-controlled epidural analgesia pump for 48 hours. In group M, magnesium sulfate, 500 mg, was added to the infusion. Measurements and Main Results: The incidence and severity of CPOP were assessed by a telephone survey 3 months after surgery. Patients were asked whether they experienced pain and to rank the severity of the pain using a 3-point scale (1, mild; 2, moderate; 3, severe). The incidences of CPOP were 42.4% in group C and 49.1% in group M. The severities of pain in the patients with CPOP were 1.0 (1-2) in group C and 1.0 (1-2) in group M. The incidence and severity of CPOP did not differ between the 2 groups. Conclusions: The epidural administration of magnesium from before the induction of anesthesia to 48 hours postoperatively did not decrease significantly the incidence or severity of CPOP in patients undergoing video-assisted thoracic surgery. (C) 2012 Elsevier Inc. All rights reserved.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Anesthesiology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.