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Catalytic Enantioselective Friedel-Crafts Alkylation of Indoles with Fumarate Derivatives in the Presence of Chiral Palladium Complexes
- Authors
- Lee, Hyun Joo; Kim, Dae Young
- Issue Date
- Jul-2012
- Publisher
- Georg Thieme Verlag
- Keywords
- Friedel-Crafts reaction; asymmetric catalysis; chiral palladium catalysts; indoles; fumamate derivatives
- Citation
- Synlett, no.11, pp 1629 - 1632
- Pages
- 4
- Journal Title
- Synlett
- Number
- 11
- Start Page
- 1629
- End Page
- 1632
- ISSN
- 0936-5214
1437-2096
- Abstract
- The catalytic enantioselective Friedel-Crafts alkylation reaction promoted by chiral palladium complexes is described. The treatment of indoles with fumarate derivatives under the mild reaction conditions afforded the corresponding Friedel-Crafts alkylation adducts with high enantioselectivities (up to 91% ee).
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Collections - College of Natural Sciences > Department of Chemistry > 1. Journal Articles
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Related Researcher
- Kim, Dae Young
- College of Natural Sciences (Department of Chemistry)