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The inhibitory effect of honokiol, a natural plant product, on vestibular schwannoma cells
- Authors
- Lee, Jong Dae; Lee, Jae Yong; Baek, Byoung Joon; Lee, Byung Don; Koh, Yoon Woo; Lee, Won-Sang; Lee, Yu-Jin; Kwon, Byoung-Mog
- Issue Date
- Jan-2012
- Publisher
- Lippincott Williams & Wilkins Ltd.
- Keywords
- Honokiol; vestibular schwannoma; apoptosis; ERK; Level of Evidence: 2c
- Citation
- Laryngoscope, v.122, no.1, pp 162 - 166
- Pages
- 5
- Journal Title
- Laryngoscope
- Volume
- 122
- Number
- 1
- Start Page
- 162
- End Page
- 166
- ISSN
- 0023-852X
1531-4995
- Abstract
- Objectives/Hypothesis: As the molecular biology of vestibular schwannoma (VS) is better understood, new means of targeting the pathways involved for intervention in schwannoma cells are being developed. Honokiol, a bioactive constituent of Magnolia officinalis, has attracted attention due to its diverse biological effects. This study was conducted to determine the inhibitory effect of honokiol on schwannoma cell proliferation.
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Related Researcher
- Lee, Jongdae
- College of Medicine (Department of Otorhinolaryngology)