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Proteomic Analysis of Hepatotoxicity Induced by Titanium Nanoparticles in Mouse Liver
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Jeon, Yu-Mi | - |
| dc.contributor.author | Park, Seul-Ki | - |
| dc.contributor.author | Lee, Mi-Young | - |
| dc.date.accessioned | 2021-08-12T04:45:48Z | - |
| dc.date.available | 2021-08-12T04:45:48Z | - |
| dc.date.issued | 2011-12 | - |
| dc.identifier.issn | 1738-2203 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/16071 | - |
| dc.description.abstract | Differentially expressed proteins in mouse liver caused by toxicity of titanium nanoparticles (TiO2 NPs) were screened. More than 1,400 protein spots in mouse liver were detected by two-dimensional gel electrophoresis, and 15 proteins that showed greater than 2-fold expressional changes in response to TiO2 NPs were identified by liquid chromatography-tandem mass spectrometry. Of these, 12 proteins were down-regulated and 3 proteins were up-regulated upon treatment with TiO2 NPs. The 15 differentially expressed proteins could be used for detection of inflammation, apoptosis, and antioxidative reaction for treatment of acute hepatic damage by TiO2 NPs. | - |
| dc.format.extent | 8 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | The Korean Society for Applied Biological Chemistry | - |
| dc.title | Proteomic Analysis of Hepatotoxicity Induced by Titanium Nanoparticles in Mouse Liver | - |
| dc.type | Article | - |
| dc.publisher.location | 대한민국 | - |
| dc.identifier.doi | 10.3839/jksabc.2011.130 | - |
| dc.identifier.wosid | 000305040500003 | - |
| dc.identifier.bibliographicCitation | Journal of the Korean Society for Applied Biological Chemistry, v.54, no.6, pp 852 - 859 | - |
| dc.citation.title | Journal of the Korean Society for Applied Biological Chemistry | - |
| dc.citation.volume | 54 | - |
| dc.citation.number | 6 | - |
| dc.citation.startPage | 852 | - |
| dc.citation.endPage | 859 | - |
| dc.type.docType | Article | - |
| dc.identifier.kciid | ART001618626 | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.description.journalRegisteredClass | kci | - |
| dc.relation.journalResearchArea | Food Science & Technology | - |
| dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
| dc.subject.keywordPlus | PROPIONYL-COA CARBOXYLASE | - |
| dc.subject.keywordPlus | MITOCHONDRIAL PROTEOME | - |
| dc.subject.keywordPlus | DIOXIDE NANOPARTICLES | - |
| dc.subject.keywordPlus | ACUTE TOXICITY | - |
| dc.subject.keywordPlus | CANCER CELLS | - |
| dc.subject.keywordPlus | MICE | - |
| dc.subject.keywordPlus | ACIDEMIA | - |
| dc.subject.keywordPlus | ALPHA | - |
| dc.subject.keywordPlus | PROLIFERATION | - |
| dc.subject.keywordPlus | DEFICIENCY | - |
| dc.subject.keywordAuthor | liver | - |
| dc.subject.keywordAuthor | mouse | - |
| dc.subject.keywordAuthor | proteomics | - |
| dc.subject.keywordAuthor | titanium nanoparticles | - |
| dc.subject.keywordAuthor | toxicity | - |
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Related Researcher
- Lee, Mi young
- College of Medical Sciences (Department of Medical Biotechnology)