The Search for Genetic Variants and Epigenetics Related to Asthma
- Authors
- Lee, Shin-Hwa; Park, Jong-Sook; Park, Choon-Sik
- Issue Date
- Oct-2011
- Publisher
- 대한천식알레르기학회
- Keywords
- Asthma; epigenetics; gene; genome; linkage; polymorphism; variants
- Citation
- Allergy, Asthma & Immunology Research, v.3, no.4, pp 236 - 244
- Pages
- 9
- Journal Title
- Allergy, Asthma & Immunology Research
- Volume
- 3
- Number
- 4
- Start Page
- 236
- End Page
- 244
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/16180
- DOI
- 10.4168/aair.2011.3.4.236
- ISSN
- 2092-7355
2092-7363
- Abstract
- For the past two decades, a huge number of genetic studies have been conducted to identify the genetic variants responsible for asthma risk. Several types of genetic and genomic approaches, including linkage analysis, candidate gene single nucleotide polymorphism studies, and whole genome-wide association studies have been applied. In this review article, the results of these approaches are summarized, and their limitations are discussed. Additionally, perspectives for applying upcoming new epigenetic or genomic technologies, such as copy number variation, are introduced to increase our understanding of new omic approaches to asthma genetics.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
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