Myocardial perfusion imaging using adenosine-induced stress dual-energy computed tomography of the heart: comparison with cardiac magnetic resonance imaging and conventional coronary angiography
- Authors
- Ko, Sung Min; Choi, Jin Woo; Song, Meong Gun; Shin, Je Kyoun; Chee, Hyun Kun; Chung, Hyun Woo; Kim, Dong Hun
- Issue Date
- Jan-2011
- Publisher
- Springer Verlag
- Keywords
- Computed tomography (CT); Coronary artery disease; Dual-energy CT; Ischaemia; Myocardial perfusion
- Citation
- European Radiology, v.21, no.1, pp 26 - 35
- Pages
- 10
- Journal Title
- European Radiology
- Volume
- 21
- Number
- 1
- Start Page
- 26
- End Page
- 35
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/16833
- DOI
- 10.1007/s00330-010-1897-1
- ISSN
- 0938-7994
1432-1084
- Abstract
- To evaluate the feasibility and diagnostic accuracy of adenosine-stress dual-energy computed tomography (DECT) for detecting haemodynamically significant stenosis causing reversible myocardial perfusion defect (PD) compared with stress perfusion magnetic resonance imaging (SP-MRI) and conventional coronary angiography (CCA). Fifty patients with known coronary artery disease (CAD) detected by dual-source CT (DSCT) were investigated by contrast-enhanced, stress DECT with high- and low-energy x-ray spectra settings during adenosine infusion. A colour-coded iodine map was used for evaluation of myocardial PDs compared with rest DSCT perfusion images. Reversible myocardial PDs according to the stress DECT/rest DSCT were compared with SP-MRI on a segmental basis and CCA on a vascular territorial basis. A total of 697 myocardial segments and 123 vascular territories of 41 patients were analysed. Three hundred one segments and 72 vascular territories in 38 patients showed reversible PDs on stress DECT. Stress DECT had 89% sensitivity, 78% specificity and 82% accuracy for detecting segments with reversible PDs seen on SP-MRI (n = 28). Compared with CCA (n = 41), stress DECT had 89% sensitivity, 76% specificity and 83% accuracy for the detection of vascular territories with reversible myocardial PDs that had haemodynamically relevant CAD. Adenosine stress DECT can identify stress-induced myocardial PD in patients with CAD.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Radiology > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/16833)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.