Relationship between vitamin K status, bone mineral density, and hs-CRP in young Korean women
DC Field | Value | Language |
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dc.contributor.author | Kim, Misung | - |
dc.contributor.author | Kim, Heeseon | - |
dc.contributor.author | Sohn, Cheongmin | - |
dc.date.accessioned | 2021-08-12T06:58:16Z | - |
dc.date.available | 2021-08-12T06:58:16Z | - |
dc.date.issued | 2010-12 | - |
dc.identifier.issn | 1976-1457 | - |
dc.identifier.issn | 2005-6168 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/17478 | - |
dc.description.abstract | Vitamin K intake has been reported as an essential factor for bone formation. The current study was conducted under the hypothesis that insufficient vitamin K intake would affect inflammatory markers and bone mineral density in young adult women. The study was a cross-sectional design that included 75 women in their 20s. Physical assessments, bone mineral density measurements, 24-hr dietary recalls, and biochemical assessments for high sensitivity C-reactive protein (hs-CRP) and percentages of undercarboxylated osteocalcin (%ucOC) were performed. An analysis of vitamin K nutritional status was performed comparing first, second, and third tertiles of intake based on %ucOC in plasma. Vitamin K intake levels in the first, second, and third tertiles were 94.88 +/- 51.48 mu g, 73.85 +/- 45.15 mu g, and 62.58 +/- 39.92 mu g, respectively (P < 0.05). The T-scores of the first and third tertiles were 1.06 and -0.03, respectively, indicating that bone mineral density was significantly lower in the group with lower vitamin K intake (P < 0.05). There was a tendency for different serum hs-CRP concentrations between the first (0.04 +/- 0.02) and third tertiles (0.11 +/- 0.18), however this was not statistically significant. Regression analysis was performed to identify the correlations between vitamin K nutritional status, inflammatory markers, and bone mineral density after adjusting for age and BMI. Serum hs-CRP concentrations were positively correlated with vitamin K deficiency status (P < 0.05). And bone mineral density, which was represented by speed, was negatively correlated with vitamin K deficiency status (P < 0.05). In conclusion, status of vitamin K affects inflammatory status and bone formation. Therefore, sufficient intake of vitamin K is required to secure peak bone mass in young adult women. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 한국영양학회 | - |
dc.title | Relationship between vitamin K status, bone mineral density, and hs-CRP in young Korean women | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.4162/nrp.2010.4.6.507 | - |
dc.identifier.scopusid | 2-s2.0-79953284969 | - |
dc.identifier.wosid | 000285823200009 | - |
dc.identifier.bibliographicCitation | Nutrition Research and Practice, v.4, no.6, pp 507 - 514 | - |
dc.citation.title | Nutrition Research and Practice | - |
dc.citation.volume | 4 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 507 | - |
dc.citation.endPage | 514 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001506208 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.subject.keywordPlus | UNDERCARBOXYLATED OSTEOCALCIN | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | TURNOVER | - |
dc.subject.keywordPlus | MARKERS | - |
dc.subject.keywordPlus | MEN | - |
dc.subject.keywordAuthor | Vitamin K | - |
dc.subject.keywordAuthor | osteocalcin | - |
dc.subject.keywordAuthor | undercarboxylated osteocalcin | - |
dc.subject.keywordAuthor | bone mineral density | - |
dc.subject.keywordAuthor | hs-CRP | - |
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