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파라벤에 의한 피부섬유아세포의 DNA 손상과 환원전리수의 억제 효과Suppressive effect of electrolyzed reduced water on the paraben-induced DNA damage in human dermal fibroblast cells
- Other Titles
- Suppressive effect of electrolyzed reduced water on the paraben-induced DNA damage in human dermal fibroblast cells
- Issue Date
- 2010
- Publisher
- 한국산학기술학회
- Keywords
- Methylparaben; Electrolyzed-reduced water; Comet assay; HDF cell
- Citation
- 한국산학기술학회논문지, v.11, no.11, pp.4427 - 4432
- Journal Title
- 한국산학기술학회논문지
- Volume
- 11
- Number
- 11
- Start Page
- 4427
- End Page
- 4432
- ISSN
- 1975-4701
- Abstract
- Parabens have been widely used as preservatives in cosmetics due to the presumed low toxicity and long history of safe use. However, recent studies have shown the potent toxicity of parabens. In order to know if electrolyzed reduced water could suppress the oxidative DNA damage of HDF cell by methylparaben, one of the frequently used parabens, we performed comet assay in this study. As a result, interestingly, electrolyzed reduced water could suppress methylparaben-induced oxidative DNA damage in HDF cells.
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Related Researcher
- Lee, Mi young
- College of Medical Sciences (Department of Medical Biotechnology)