Standard vs magnifying narrow-band imaging endoscopy for diagnosis of Helicobacter pylori infection and gastric precancerous conditions
- Authors
- Cho, Jun-Hyung; Jeon, Seong Ran; Jin, So-Young; Park, Suyeon
- Issue Date
- 14-May-2021
- Publisher
- Baishideng Publishing Group
- Keywords
- Endoscopy; Magnifying narrow-band imaging; Helicobacter pylori; Gastric atrophy; Intestinal metaplasia; Pepsinogen
- Citation
- World Journal of Gastroenterology, v.27, no.18, pp 2238 - 2250
- Pages
- 13
- Journal Title
- World Journal of Gastroenterology
- Volume
- 27
- Number
- 18
- Start Page
- 2238
- End Page
- 2250
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/18839
- DOI
- 10.3748/wjg.v27.i18.2238
- ISSN
- 1007-9327
2219-2840
- Abstract
- BACKGROUND Advances in endoscopic imaging enable the identification of patients at high risk of gastric cancer. However, there are no comparative data on the utility of standard and magnifying narrow-band imaging (M-NBI) endoscopy for diagnosing Helicobacter pylori (H. pylori) infection, gastric atrophy, and intestinal metaplasia. AIM To compare the diagnostic performance of standard and M-NBI endoscopy for H. pylori gastritis and precancerous conditions. METHODS In 254 patients, standard endoscopy findings were classified into mosaic-like appearance (type A), diffuse homogenous redness (type B), and irregular redness with groove (type C). Gastric mucosal patterns visualized by M-NBI were classified as regular round pits with polygonal sulci (type Z-1), more dilated and linear pits without sulci (type Z-2), and loss of gastric pits with coiled vessels (type Z-3). RESULTS The diagnostic accuracy of standard and M-NBI endoscopy for H. pylori gastritis was 93.3% and 96.1%, respectively. Regarding gastric precancerous conditions, the accuracy of standard and M-NBI endoscopy was 72.0% vs 72.6% for moderate to severe atrophy, and 61.7% vs. 61.1% for intestinal metaplasia in the corpus, respectively. Compared to type A and Z-1, types B+C and Z-2+Z-3 were significantly associated with moderate to severe atrophy [odds ratio (OR) = 5.56 and 8.67] and serum pepsinogen I/II ratio of <= 3 (OR = 4.48 and 5.69). CONCLUSION Close observation of the gastric mucosa by standard and M-NBI endoscopy is useful for the diagnosis of H. pylori gastritis and precancerous conditions.
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Collections - College of Medicine > Department of Pathology > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
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