Comparison of Automated Brain Volume Measures by NeuroQuant vs. Freesurfer in Patients with Mild Cognitive Impairment: Effect of Slice Thickness
DC Field | Value | Language |
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dc.contributor.author | Yim, Younghee | - |
dc.contributor.author | Lee, Ji Young | - |
dc.contributor.author | Oh, Se Won | - |
dc.contributor.author | Chung, Mi Sun | - |
dc.contributor.author | Park, Ji Eun | - |
dc.contributor.author | Moon, Yeonsil | - |
dc.contributor.author | Jeon, Hong Jun | - |
dc.contributor.author | Moon, Won-Jin | - |
dc.date.accessioned | 2021-09-10T05:51:01Z | - |
dc.date.available | 2021-09-10T05:51:01Z | - |
dc.date.issued | 2021-03 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.issn | 1976-2437 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/18972 | - |
dc.description.abstract | Purpose: This study aimed to examine the inter-method reliability and volumetric differences between NeuroQuant (NQ) and Freesurfer (FS) using Tl volume imaging sequence with different slice thicknesses in patients with mild cognitive impairment (MCI). Materials and Methods: This retrospective study enrolled 80 patients diagnosed with MCI at our memory clinic. NQ and FS were used for volumetric analysis of three-dimensional Tl -weighted images with slice thickness of 1 and 1.2 mm. Inter-method reliability was measured with Pearson correlation coefficient (r), intraclass correlation coefficient (ICC), and effect size (ES). Results: Overall, NQ volumes were larger than FS volumes in several locations: whole brain (0.78%), cortical gray matter (5.34%), and white matter (2.68%). Volume measures by NQ and FS showed good-to-excellent ICCs with both 1 and 1.2 mm slice thickness (ICC=0.75-0.97, ES=-1.0-0.73 vs. ICC=0.78-0.96, ES=-0.9-0.77, respectively), except for putamen, palfidum, thalamus, and total intracranial volumes. The ICCs in all locations, except the putamen and cerebellum, were slightly higher with a slice thickness of 1 mm compared to those of 1.2 mm. Conclusion: Inter-method reliability between NQ and FS was good-to-excellent in most regions with improvement with a 1-mm slice thickness. This finding indicates that the potential effects of slice thickness should be considered when performing volumetric measurements for cognitive impairment. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 연세대학교의과대학 | - |
dc.title | Comparison of Automated Brain Volume Measures by NeuroQuant vs. Freesurfer in Patients with Mild Cognitive Impairment: Effect of Slice Thickness | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3349/ymj.2021.62.3255 | - |
dc.identifier.wosid | 000621963800009 | - |
dc.identifier.bibliographicCitation | Yonsei Medical Journal, v.62, no.3, pp 255 - 261 | - |
dc.citation.title | Yonsei Medical Journal | - |
dc.citation.volume | 62 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 255 | - |
dc.citation.endPage | 261 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002685138 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | MRI | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordAuthor | Brain volume | - |
dc.subject.keywordAuthor | FreeSurfer | - |
dc.subject.keywordAuthor | mild cognitive impairment | - |
dc.subject.keywordAuthor | NeuroQuant | - |
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