Increased atrial fibrillation risk in Parkinson's disease: A nationwide population-based study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Han, Seokmoon | - |
dc.contributor.author | Moon, Inki | - |
dc.contributor.author | Choi, Eue-Keun | - |
dc.contributor.author | Han, Kyung-Do | - |
dc.contributor.author | Cho, Hae-Chan | - |
dc.contributor.author | Lee, Seo-Young | - |
dc.contributor.author | Yang, Seokhun | - |
dc.contributor.author | Kwon, Soonil | - |
dc.contributor.author | Choi, You-jung | - |
dc.contributor.author | Lee, Hyun-Jung | - |
dc.contributor.author | Lee, Euijae | - |
dc.contributor.author | Lee, So-Ryung | - |
dc.contributor.author | Oh, Seil | - |
dc.date.accessioned | 2021-09-10T06:25:47Z | - |
dc.date.available | 2021-09-10T06:25:47Z | - |
dc.date.issued | 2021-01 | - |
dc.identifier.issn | 2328-9503 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/19029 | - |
dc.description.abstract | Objective: Parkinson's disease (PD) is the second most common neurodegenerative disorder associated with various morbidities. Although the relationship between cardiovascular disease and PD has been studied, a paucity of information on PD and atrial fibrillation (AF) association exists. Thus, we aimed to investigate whether patients with PD have an increased risk of AF. Methods: This study included 57,585 patients with newly diagnosed PD (>= 40-year-old, mean age 69.7 years, men 40.2%) and without a history of AF from the Korean National Health Insurance Service (NHIS) database between 2010 and 2015. Furthermore, an equal number of age- and sex-matched subjects without PD were selected for comparison. The primary outcome was new-onset AF. Results: During the mean follow-up period of 3.4 +/- 1.8 years, AF was newly diagnosed in 3,665 patients. A significantly higher incidence rate of AF was noted among patients with PD than among patients without PD (10.75 and 7.86 per 1000 person-year, respectively). Multivariate Cox-regression analysis revealed that PD was an independent risk factor for AF (hazard ratio [HR]: 1.27, 95% confidence interval [CI]: 1.18-1.36). Furthermore, subgroup analyses revealed that AF risk was higher in the younger age subgroups, and compared with the non-PD group, the youngest PD group (age: 40-49 years) had a threefold increased risk of AF (HR: 3.06, 95% CI: 1.20-7.77). Interpretation: Patients with PD, especially the younger age subgroups, have an increased risk of AF. Active surveillance and management of AF should be considered to prevent further complications. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | John Wiley and Sons Ltd | - |
dc.title | Increased atrial fibrillation risk in Parkinson's disease: A nationwide population-based study | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1002/acn3.51279 | - |
dc.identifier.scopusid | 2-s2.0-85099069984 | - |
dc.identifier.wosid | 000604103300001 | - |
dc.identifier.bibliographicCitation | Annals of Clinical and Translational Neurology, v.8, no.1, pp 238 - 246 | - |
dc.citation.title | Annals of Clinical and Translational Neurology | - |
dc.citation.volume | 8 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 238 | - |
dc.citation.endPage | 246 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | NONMOTOR SYMPTOMS | - |
dc.subject.keywordPlus | ONSET | - |
dc.subject.keywordPlus | DYSAUTONOMIA | - |
dc.subject.keywordPlus | SCINTIGRAPHY | - |
dc.subject.keywordPlus | CONDUCTION | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.