Microstructures and biological properties of 3D-printed titanium intervertebral spacer with the tri-calcium phosphate loaded demineralized bone matrix hydrogel
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Hoe-Jin | - |
dc.contributor.author | Hossain, Mosharaf | - |
dc.contributor.author | Park, Seong-Su | - |
dc.contributor.author | Im, Soo-Bin | - |
dc.contributor.author | Lee, Byong-Taek | - |
dc.date.accessioned | 2021-10-05T04:41:05Z | - |
dc.date.available | 2021-10-05T04:41:05Z | - |
dc.date.issued | 2021-11-15 | - |
dc.identifier.issn | 0167-577X | - |
dc.identifier.issn | 1873-4979 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/19795 | - |
dc.description.abstract | The aim of this study was to improve the osteogenic ability of 3D-printed porous titanium (Ti) intervertebral spacer with a Tri-calcium Phosphate (TCP) loaded Demineralized Bone Matrix Hydrogel (DBM). Microstructures and morphologies of Ti, DBM loaded Ti (Ti/DBM), and TCP and DBM loaded Ti (Ti/DBM/TCP) scaffolds were characterized by SEM and EDX. In-vitro studies showed that Ti/DBM/TCP scaffold was biocompatible and could promote osteogenesis by up-regulating the expression of bone-related genes. Furthermore, the results of in-vivo studies using rabbit-femur defect model revealed that the implanted Ti/DBM/TCP scaffold had superior bone regeneration. The TCP and DBM loading were an effective approach of inducing osteogenesis in 3D-printed Ti intervertebral spacer by providing favorable osteogenic differentiation conditions and promoting bone formation. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier BV | - |
dc.title | Microstructures and biological properties of 3D-printed titanium intervertebral spacer with the tri-calcium phosphate loaded demineralized bone matrix hydrogel | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.doi | 10.1016/j.matlet.2021.130519 | - |
dc.identifier.scopusid | 2-s2.0-85111316276 | - |
dc.identifier.wosid | 000686905400004 | - |
dc.identifier.bibliographicCitation | Materials Letters, v.303, no.0, pp 1 - 4 | - |
dc.citation.title | Materials Letters | - |
dc.citation.volume | 303 | - |
dc.citation.number | 0 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 4 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.subject.keywordAuthor | 3D-printed titanium cage | - |
dc.subject.keywordAuthor | Intervertebral spacer | - |
dc.subject.keywordAuthor | Demineralized bone matrix | - |
dc.subject.keywordAuthor | Tri-calcium phosphate | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(31538) 22, Soonchunhyang-ro, Asan-si, Chungcheongnam-do, Republic of Korea+82-41-530-1114
COPYRIGHT 2021 by SOONCHUNHYANG UNIVERSITY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.