주요우울장애 환자에서 자살사고 동반 여부에 따른 부적격 짝맞추기 음성파의 비교Comparison of Mismatch Negativity According to Suicidal Ideation in Patients With Major Depressive Disorder
- Other Titles
- Comparison of Mismatch Negativity According to Suicidal Ideation in Patients With Major Depressive Disorder
- Authors
- 이민지; 이연정; 황재욱; 우성일; 김민재; 강병주; 김영근; 한상우
- Issue Date
- Oct-2021
- Publisher
- 대한불안의학회
- Keywords
- 부적격 짝맞추기 음성파; 자살사고; 주요우울증.; Mismatch negativity; Suicidal ideation; Major depressive disorder.
- Citation
- 대한불안의학회지, v.17, no.2, pp 84 - 91
- Pages
- 8
- Journal Title
- 대한불안의학회지
- Volume
- 17
- Number
- 2
- Start Page
- 84
- End Page
- 91
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/20002
- DOI
- 10.24986/anxmod.2021.17.2.006
- ISSN
- 2586-0151
2586-0046
- Abstract
- Objective : Mismatch negativity (MMN) is known to reflect several abnormalities of cognitive functioning.
This study is aimed to investigate the differences in MMN among major depressive disorder (MDD) patients with or without suicidal ideation.
Methods : Sixty-seven patients with MDD were recruited into this study. MMN was measured by a 64-channel electroencephalography (EEG) using oddball paradigm over the front-central area. Clinical characteristics were assessed using the Beck Anxiety Inventory (BAI), the Beck Depression Inventory-II (BDIII), and the Beck Scale for Suicide ideation (SSI-BECK). Patients were divided into two groups, no suicidal ideation (N=12) and suicidal ideation (N=55), depending on the presence of suicide ideation in SSI-BECK questionnaires.
Results : The MMN latencies were significantly longer in the MDD patients with suicidal ideation than in the MDD patents without suicidal ideation (p<0.05). The MMN amplitudes were not significantly different between the two groups.
Conclusion : Suicidal ideation may be associated with longer MMN latencies, and it suggests that MMN may play a potential role in assessing the suicidal risk among MDD patients. (Anxiety and Mood 2021; 17(2):84-91)
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