Abdominal periaortic and renal sinus fat attenuation indices measured on computed tomography are associated with metabolic syndrome
- Authors
- Lee, Eun Ji; Cho, Nam-Jun; Kim, Hyoungnae; Nam, Boda; Jeon, Jin Seok; Noh, Hyunjin; Han, Dong Cheol; Kim, Sang Hyun; Kwon, Soon Hyo
- Issue Date
- Jan-2022
- Publisher
- Springer Verlag
- Keywords
- Obesity; Metabolic syndrome; Adipose tissue; Intra-abdominal fat; Multidetector computed tomography
- Citation
- European Radiology, v.32, no.1, pp 395 - 404
- Pages
- 10
- Journal Title
- European Radiology
- Volume
- 32
- Number
- 1
- Start Page
- 395
- End Page
- 404
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/20255
- DOI
- 10.1007/s00330-021-08090-7
- ISSN
- 0938-7994
1432-1084
- Abstract
- Objectives To investigate the association between abdominal periaortic (APA) and renal sinus (RS) fat attenuation index (FAI) measured on MDCT and metabolic syndrome in non-obese and obese individuals. Methods Visceral, subcutaneous, RS, and APA adipose tissue were measured in preoperative abdominal CT scans of individuals who underwent donor nephrectomy (n = 84) or bariatric surgery (n = 155). FAI was defined as the mean attenuation of measured fat volume. Participants were categorized into four groups: non-obese without metabolic syndrome (n = 64), non-obese with metabolic syndrome (n = 25), obese without metabolic syndrome (n = 21), and obese with metabolic syndrome (n = 129). The volume and FAI of each fat segment were compared among the groups. Receiver operator characteristics curve analysis was used to assess the association between the FAIs and metabolic syndrome. Results FAIs of all abdominal fat segments were significantly lower in the obese group than in the non-obese group (p < 0.001). RS, APA, and the visceral adipose tissue FAIs were significantly lower in participants with metabolic syndrome than in those without metabolic syndrome in the non-obese group (p < 0.001, p = 0.006, and p < 0.001, respectively). The area under the curve for predicting metabolic syndrome was significantly higher for APA FAI (0.790) than subcutaneous, visceral, and RS FAI in all groups (0.649, 0.647, and 0.655, respectively). Conclusion Both metabolic syndrome and obesity were associated with lower RS and APA adipose tissue FAI, and APA FAI performed best for predicting metabolic syndrome.
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Collections - College of Medicine > Department of General Surgery > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
- College of Medicine > Department of Radiology > 1. Journal Articles
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