Recent patents in allergy and immunology: A quantitative real-time polymerase chain reaction method for diagnosing asthma and asthma exacerbation
DC Field | Value | Language |
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dc.contributor.author | Lee, Pureun-Haneul | - |
dc.contributor.author | Choi, SeonMuk | - |
dc.contributor.author | An, MinHyeok | - |
dc.contributor.author | Jang, An-Soo | - |
dc.date.accessioned | 2022-04-21T02:40:18Z | - |
dc.date.available | 2022-04-21T02:40:18Z | - |
dc.date.issued | 2022-04-01 | - |
dc.identifier.issn | 2045-7022 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/20655 | - |
dc.description.abstract | Background: Asthma is diagnosed based on a history of the characteristic symptoms and evidence of expiratory airflow limitation. However, asthma diagnosis using the existing tests is associated with a risk of coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 spread. In this study, we developed a quantitative real-time polymerase chain reaction (qRT-PCR)-based asthma diagnosis tool. Methods: We detected nectin-4 in the plasma of patients with asthma using qRT-PCR, explored the relationship of clinical variables. Results: quantitative real-time polymerase chain reaction revealed that plasma nectin-4 mRNA levels were higher in asthmatics than controls. These results correlated with lung function. Conclusions: Those results suggest that qRT-PCR for nectin-4 may aid asthma diagnosis and monitoring. | - |
dc.format.extent | 3 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | BioMed Central | - |
dc.title | Recent patents in allergy and immunology: A quantitative real-time polymerase chain reaction method for diagnosing asthma and asthma exacerbation | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1002/clt2.12136 | - |
dc.identifier.scopusid | 2-s2.0-85128720716 | - |
dc.identifier.wosid | 000776510800001 | - |
dc.identifier.bibliographicCitation | Clinical and Translational Allergy, v.12, no.4, pp 1 - 3 | - |
dc.citation.title | Clinical and Translational Allergy | - |
dc.citation.volume | 12 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 3 | - |
dc.type.docType | Letter | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Allergy | - |
dc.relation.journalWebOfScienceCategory | Allergy | - |
dc.subject.keywordAuthor | asthma | - |
dc.subject.keywordAuthor | diagnosis | - |
dc.subject.keywordAuthor | nectin-4 | - |
dc.subject.keywordAuthor | qRT-PCR | - |
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