Histological Diagnostic Yield and Clinical Significance of the First Biopsy in Device-Assisted Enteroscopy in Patients with Small Bowel Diseases: A KASID Multicenter Studyopen access
- Authors
- Goong, Hyeon Jeong; Kim, Tae Joon; Nam, Kwangwoo; Park, Jihye; Kim, Jin-Oh; Kim, Hyun Gun; Ko, Bong Min; Jeon, Seong Ran
- Issue Date
- Apr-2022
- Publisher
- MDPI AG
- Keywords
- device assisted enteroscopy; small bowel; biopsy
- Citation
- Diagnostics, v.12, no.4, pp 1 - 10
- Pages
- 10
- Journal Title
- Diagnostics
- Volume
- 12
- Number
- 4
- Start Page
- 1
- End Page
- 10
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/20729
- DOI
- 10.3390/diagnostics12040964
- ISSN
- 2075-4418
- Abstract
- Device-assisted enteroscopy (DAE) enables the direct visualization of small bowel lesions with histological diagnosis; however, few studies have described the diagnostic performance of enteroscopic biopsy. We investigated the diagnostic performance of enteroscopic biopsy. We used a nationwide multicenter enteroscopy database to identify patients who underwent DAE with biopsy for small bowel diseases. The patients were classified into the tumor and non-tumor groups according to the final diagnosis. They were also divided into diagnostic and non-diagnostic groups based on the enteroscopic biopsy results. The clinical significance of the first biopsy and histological diagnostic yield of DAE were analyzed. Among the 112 procedures investigated, 32 (28.9%) were diagnosed with tumors, and 80 (71.7%) were diagnosed with non-tumor diseases. The overall histological diagnostic yield of DAE was 43.7%. The histological diagnostic yield was significantly higher in the tumor than in the non-tumor group (81.2% vs. 28.8%, p < 0.001). The mean number of biopsies was significantly higher in the diagnostic than in the non-diagnostic group (5.6 +/- 3.3 vs. 3.7 +/- 2.1, p = 0.001). In the diagnostic group, 87.7% of the cases were histologically confirmed at the first biopsy. Therefore, the first biopsy should be performed carefully.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
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