Assessment of vitamin D, exercise, and lipid profile associated with excessive daytime sleepiness in school children
- Authors
- Sung, Myongsoon; Rhie, Seonkyeong; Kim, Ju Hee; Lee, Seung Won; Ha, Eun Kyo; Jee, Hye Mi; Yoo, Eun-Gyong; Chae, Kyu Young; Han, Man Yong
- Issue Date
- Jan-2021
- Publisher
- Elsevier BV
- Keywords
- Excessive daytime sleepiness; Children; Serum 25-hydroxyvitamin D-3; Body mass index; Regular exercise
- Citation
- Sleep Medicine, v.77, pp 51 - 57
- Pages
- 7
- Journal Title
- Sleep Medicine
- Volume
- 77
- Start Page
- 51
- End Page
- 57
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/2105
- DOI
- 10.1016/j.sleep.2020.11.017
- ISSN
- 1389-9457
1878-5506
- Abstract
- Previous research reported associations of excessive daytime sleepiness (EDS) with a low vitamin D level, obesity, and sexual maturity. The aim of this study was to identify the association and rank the importance of these with EDS. This study examined 618 children who were 10-12 year-old. The pediatric daytime sleepiness scale (PDSS) was used to evaluate EDS and sleep patterns. EDS was defined as a total PDSS score above 17. We ranked the importance of the relationship of these factors with EDS using random forest analysis. EDS (n = 111, 18%) was positively associated with more advanced pubertal stage in girls, chronic cough, urticaria, and allergic rhinitis. Multivariable analysis with adjustment for confounding indicated that children with low level of 25-hydroxyvitaminD 3 (25(OH)D-3 (<20 ng/mL) and high-density lipoprotein-cholesterol (HDL-C) (<40 mg/dL) levels had an increased risk of EDS (25(OH) D-3:adjusted odds ratio [aOR] = 1.73; 95% confidence interval [CI]: 1.06 to 2.81; P = 0.028; HDL-C: aOR = 2.84; 95% CI: 1.05 to 7.68; P = 0.039). Random forest analysis indicated that 25(OH)D-3 level, exercise, and body mass index (BMI) were over three. This study indicated high levels of 25-(OH)D-3 and HDL-C and performing regular exercise decreased the risk of EDS. (C) 2020 Elsevier B.V. All rights reserved.
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Collections - College of Medicine > Department of Pediatrics > 1. Journal Articles
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