Local complications are related to poor long-term outcome in patients undergoing curative gastrectomy for advanced gastric cancerLocal complications are related to poor long-term outcome in patients undergoing curative gastrectomy for advanced gastric cancer
- Other Titles
- Local complications are related to poor long-term outcome in patients undergoing curative gastrectomy for advanced gastric cancer
- Authors
- 하태선; 조규석; 신응진; 류승완; Ryu Keun Won; 김민찬; 형우진; 김찬영; 이혁준; 신동우; 이준호
- Issue Date
- Jun-2022
- Publisher
- 대한종양외과학회
- Keywords
- Stomach neoplasms; Postoperative complication; Tumor recurrence
- Citation
- 대한종양외과학회지, v.18, no.1, pp 36 - 46
- Pages
- 11
- Journal Title
- 대한종양외과학회지
- Volume
- 18
- Number
- 1
- Start Page
- 36
- End Page
- 46
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21171
- DOI
- 10.14216/kjco.22005
- ISSN
- 2288-4084
- Abstract
- Purpose: The present study was performed to investigate the effects of local complications (LC) on long-term survival and cancer recurrence in patients undergoing curative gastrectomy for gastric cancer.Methods: We analyzed 2,627 patients after curative gastrectomy for gastric cancer between January 2001 and December 2006. Patients were classified into groups no complications (NC), LC, or systemic complications (SC).Results: Among the 2,627 patients, 475 patients developed complications (LC group [n=374, 14.2%] and SC group [n=101, 3.9%]). The 5-year cancer-specific survival rate was significantly poorer in the LC group compared to the NC and SC groups (LC, 78.0%; NC, 85.4%; SC, 80.2%; P=0.007). The occurrence of LC was identified as a significant independent prognostic factor for overall and cancer-specific survival (hazard ratio [HR], 2.08; 95% confidence interval [CI], 1.46–2.97; P=0.001 and HR, 1.77; 95% CI, 1.12–2.81; P=0.015). The tumor recurrence rates were higher in the LC group than the in other two groups (LC, 23.5%; NC, 15.4%; SC, 15.8%; P<0.001). The occurrence of LC was an independent predictor of tumor recurrence in patients undergoing curative gastrectomy for gastric cancer (HR, 1.55; 95% CI, 1.11–2.17; P=0.011).Conclusion: LC are associated with adverse long-term outcomes in patients after curative gastrectomy for advanced gastric cancer.
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Collections - College of Medicine > Department of General Surgery > 1. Journal Articles
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