Acute Hepatitis A-Induced Autoimmune Hepatitis: A Case Report and Literature Reviewopen access
- Authors
- Jo, Hye In; Kim, Minchang; Yoo, Jeong-Ju; Kim, Sang Gyune; Kim, Young Seok; Chin, Susie
- Issue Date
- Jul-2022
- Publisher
- MDPI
- Keywords
- acute hepatitis A; autoimmune hepatitis; jaundice
- Citation
- Medicina (Kaunas, Lithuania), v.58, no.7, pp 1 - 7
- Pages
- 7
- Journal Title
- Medicina (Kaunas, Lithuania)
- Volume
- 58
- Number
- 7
- Start Page
- 1
- End Page
- 7
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21300
- DOI
- 10.3390/medicina58070845
- ISSN
- 1010-660X
1648-9144
- Abstract
- Introduction: The pathogenesis of autoimmune hepatitis (AIH) is little known. Previous case reports suggest that several viral hepatitis, including hepatitis A, can trigger AIH. Patient: A 55-year-old female showed general weakness and jaundice. The patient was diagnosed with acute hepatitis A and discharged after 14 days of hospitalization with improving liver function. However, blood tests performed 6 days after discharge revealed an increase in liver enzymes and high serum titers of an anti-nuclear antibody and immunoglobulin G. She was readmitted for liver biopsy. Diagnosis: Liver biopsy showed acute hepatitis A along with AIH. According to the revised international autoimmune hepatitis group scoring system, her score was 14 and she was diagnosed as AIH induced by acute hepatitis A. Intervention: Conservative treatments with crystalloid (Lactated Ringer's Solution), ursodeoxycholic acid, and silymarin were administered. Outcomes: The patient has been followed up on an outpatient basis and neither symptom recurrence nor an increase in liver enzymes has been reported thus far. Lessons: After the treatment of acute hepatitis A, liver function needs to be carefully monitored over time, and the possibility of autoimmune hepatitis should be considered when liver enzymes increases.
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Collections - College of Medicine > Department of Pathology > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
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