Assessment of Disease Severity and Quality of Life in Patients with Atopic Dermatitis from South KoreaAssessment of Disease Severity and Quality of Life in Patients with Atopic Dermatitis from South Korea
- Other Titles
- Assessment of Disease Severity and Quality of Life in Patients with Atopic Dermatitis from South Korea
- Authors
- 손상욱; 이지현; 안지영; 장성은; 최응호; 한태영; 장용현; 김혜원; 김문범; 김유찬; 고현창; 고주연; 이상은; 이양원; 유박린; 나찬호; 박창욱; 박천욱; 박귀영; 박건; 박영립; 노주영; 서영준; 신민경; 이수진; 조상현
- Issue Date
- Dec-2022
- Publisher
- 대한피부과학회
- Keywords
- Anxiety; Atopic dermatitis; Depression; Quality of life
- Citation
- Annals of Dermatology, v.34, no.6, pp 419 - 430
- Pages
- 12
- Journal Title
- Annals of Dermatology
- Volume
- 34
- Number
- 6
- Start Page
- 419
- End Page
- 430
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21830
- ISSN
- 1013-9087
2005-3894
- Abstract
- Background: Data illustrating the impact of atopic dermatitis (AD) on lives of adults withAD in South Korea are limited.
Objective: To assess the AD disease severity and its impact on quality of life (QoL) in patientswith AD from South Korea.
Methods: Patients with AD utilizing the specialist dermatology services of major hospitals inSouth Korea were assessed for disease severity using Eczema Area and Severity Index (EASI)score, for QoL using Dermatology Life Quality Index (DLQI) (for QoL), and for comorbiditiesand treatment experience via retrospective review of 12-month medical records. Clinical andsociodemographic characteristics were also measured.
Results: Of the 1,163 patients, 695 (59.8%) were men (mean age [years]±standard devia-tion: 31.6±12.1). Overall, 52.9% (n=615) patients had moderate-to-severe disease (EASI>7).
The QoL of 72.3% (n=840) patients was affected moderately-to-severely (DLQI score: 6~30).
Systemic immunosuppressants were used ≥1 over past 12 months in 51.9% (n=603) patients,and the most commonly used were cyclosporines (45.7%, n=531) and systemic corticosteroids(40.5%, n=471). Approximately, 10.8% (n=126) patients consulted or received treatment forAD-related eye problem. Of these, 40% (n=50) patients reported poor, very poor, or complete-ly blind status; approximately, 16.7% patients (n=192) reported having depression or anxiety;and 35.5% (n=410) reported suicidal ideation or suicidal attempt.
Conclusion: A large proportion of patients had moderate-to-severe AD, a compromisedQoL, and ocular or mental health comorbidities, indicating a high disease burden despite sys-temic treatment. These findings highlight the importance of a holistic approach for the evalu-ation and treatment of patients with AD.
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