A long-term follow-up study of diabetic foot ulcer using micronized acellular dermal matrixopen access
- Authors
- Byeon, Je Yeon; Hwang, Yong Seon; Choi, Hwan Jun; Kim, Jun Hyuk; Lee, Da Woon
- Issue Date
- Jan-2022
- Publisher
- Blackwell Publishing Inc.
- Keywords
- acellular dermis; diabetic foot; recurrence; therapeutics; ulcer
- Citation
- International Wound Journal
- Journal Title
- International Wound Journal
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/21911
- DOI
- 10.1111/iwj.14018
- ISSN
- 1742-4801
1742-481X
- Abstract
- Treating a diabetic foot ulcer (DFU) extending to the tendon or bone can be a challenge for physicians. Recent studies have shown positive results of micronized acellular dermal matrix (ADM) treatment for treating DFU. However, studies on such ADM with a long-term follow-up are rare. Thus, the objective of this study was to retrospectively analyse patients treated with micronized ADM with a long-term follow-up to assess the effectiveness of the treatment and determine the recurrence rate. The rate of success of complete healing was 62.96% and the time of complete healing was 86.96 days in this study. The recurrence rate of DFUs was 41.17% in the overall group. However, it was only 23.52% in the micronized ADM group. The average duration of recurrence was 720.50 +/- 505.12 days. The recurrence rate was 50% in weight bearing areas such as the plantar and heel. It was 12.5% in toes and non-weight bearing areas. In conclusion, micronized ADM can be used to effectively treat DFUs that have invaded ligaments or bones. A close follow-up of weight bearing area wounds will allow us to identify and treat recurrence early.
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Collections - College of Medicine > Department of Plastic Surgery > 1. Journal Articles
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