Sex Differences in Delayed Hospitalization in Patients with Non-ST-Segment Elevation Myocardial Infarction Undergoing New-Generation Drug-Eluting Stent Implantationopen access
- Authors
- Kim, Yong Hoon; Her, Ae-Young; Rha, Seung-Woon; Choi, Cheol Ung; Choi, Byoung Geol; Kim, Ji Bak; Park, Soohyung; Kang, Dong Oh; Park, Ji Young; Choi, Woong Gil; Park, Sang-Ho; Jeong, Myung Ho
- Issue Date
- Mar-2023
- Publisher
- MDPI AG
- Keywords
- non-ST-elevation myocardial infarction; sex discrepancies; prehospital delay
- Citation
- Journal of Clinical Medicine, v.12, no.5
- Journal Title
- Journal of Clinical Medicine
- Volume
- 12
- Number
- 5
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/22358
- DOI
- 10.3390/jcm12051982
- ISSN
- 2077-0383
2077-0383
- Abstract
- We compared the effects of sex differences in delayed hospitalization (symptom-to-door time [SDT], >= 24 h) on major clinical outcomes in patients with non-ST-segment elevation myocardial infarction after new-generation drug-eluting stent implantation. A total of 4593 patients were classified into groups with (n = 1276) and without delayed hospitalization (SDT < 24 h, n = 3317). Thereafter, these two groups were subdivided into male and female groups. The primary clinical outcomes were major adverse cardiac and cerebrovascular events (MACCE), defined as all-cause death, recurrent myocardial infarction, repeat coronary revascularization, and stroke. The secondary clinical outcome was stent thrombosis. After multivariable- and propensity score-adjusted analyses, in-hospital mortalities were similar between the male and female groups in both the SDT < 24 h and SDT >= 24 h groups. However, during a 3-year follow-up period, in the SDT < 24 h group, all-cause death (p = 0.013 and p = 0.005, respectively) and cardiac death (CD, p = 0.015 and p = 0.008, respectively) rates were significantly higher in the female group than those in the male group. This may be related to the lower all-cause death and CD rates (p = 0.022 and p = 0.012, respectively) in the SDT < 24 h group than in the SDT >= 24 h group among male patients. Other outcomes were similar between the male and female groups and between the SDT < 24 h and SDT >= 24 h groups. In this prospective cohort study, female patients showed higher 3-year mortality, especially in the SDT < 24 h, compared to male patients.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/22358)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.